First Generation of Cannabis sativa Stem Cells: Nourishing the Skin Microbiota

Ò. Expósito, A. Guirado, D. Robustillo, A. Gallego, M. Mas, P. Riera, D. Luna, S. Laplana, T. Ruiz, K. Lingen

The skin microbiota and the brain are connected through an existing natural pathway where the microbiota is the first step.
The new active Kannabia SensePLF (INCI name: Cannabis Sativa Callus Lysate), is the first generation of Cannabis sativa plant
stem cells and introduces the concept of in-situ postbiotic. Through its mechanism of action, the active modulates the skin commensal
microbiota to produce a positive in-situ postbiotic cocktail that ignites the synthesis of happiness related neurochemicals from the skin that connects with the brain, turning into a well-being response and a healthier and stronger skin. Several in vitro and in vivo trials have been carried out to demonstrate the skin well-ageing effect, positive brain activation and modulation of mood state thanks to the active ingredient.

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