U.S. Patent 10,897,899

INOLEX is pleased to announce its recently issued patent that claims multifunctional preservation systems comprising caprylhydroxamic acid (CHA) and select diols for cosmetics, personal care, and pharmaceuticals. The patent claims the use of these ingredient compositions in formulations as well as blends comprising the CHA-diol compositions.

Caprylhydroxamic acid is a 100% natural and readily biodegradable chelating agent derived from coconut-sourced caprylic acid. CHA is a biostatic ingredient that provides a strong hurdle to microbial growth across a wide pH range (pH 4-8). Robust broad spectrum protection against contamination by bacteria, yeast, and mold is achieved via combination of CHA with medium chain terminal diols, such as caprylyl glycol, glyceryl caprylate, or caprylyl glyceryl ether.

“We have been advancing the industry with innovative preservation approaches for over two decades,” said David Plimpton, CEO and President of INOLEX. “This latest patent demonstrates our leadership in this category. Our broad portfolio of CHA offerings exemplifies our drive to bring effective alternative preservation mainstream.”

The company offers its portfolio of CHA-diol broad spectrum systems under the Spectrastat™ brand, with particular emphasis on 100% natural systems, such as Spectrastat™ G2 Natural MB (INCI: Caprylhydroxamic Acid (and) Glyceryl Caprylate (and) Glycerin).

The patent granted recognizes INOLEX’s ongoing commitment to innovation in the field of safe, effective, and sustainable options for preservation of formulated products. In October 2020, the Cosmetic Ingredient Review (CIR) released its final report on the safety of caprylhydroxamic acid as used in cosmetics, in which the independent Expert Panel for Cosmetic Ingredient Safety concluded that CHA is safe as used in the present practices of the industry. This conclusion further validated the outstanding track record of safety associated with CHA.

According to Dr. Michael Fevola, Vice President of Research & Development at INOLEX, “As a company we have established high safety and transparency standards for all of our technologies. We proactively contributed our entire archive of safety and toxicological data on CHA for the benefit of our customers and their consumers. INOLEX also commissioned additional clinical safety studies and a quantitative risk assessment as requested by the Expert Panel to validate CHA safety at all use levels reported by CIR.”

To date, the use of CHA has been reported in over 5,000 product SKUs around the world, as documented by the Mintel Global New Products Database.


INOLEX Ingredients
The INOLEX innovation platform is guided by the Principles of Green Chemistry and life-cycle thinking. The company is recognized for its leading proprietary technologies—with an emphasis on natural, plant-based solutions—in Alternative Preservation, Silicone Alternatives, Palm Alternatives, Film Formers, and Conditioning Agents. INOLEX is a member of the Roundtable on Sustainable Palm Oil (RSPO), is RSPO Supply Chain Certified, and offers 100% of its palm-derived products as RSPO Mass Balance.

Notable product innovation awards include the 2020 Sustainability Award from Henkel Beauty, presented during the 2020 ACI Annual Meeting in Orlando, for LexFeel™ D5, a sustainable, highperformance silicone alternative ingredient; the 2020 HPCI Innovation Award for AminoSensyl™ Amino Lipid Platform of 100% natural, quat-free conditioning ingredients; the 2018 ITEHPEC Innovation Award in LATAM for LexFeel™ Vibrant, a patented color-enhancing sensory agent; Finalist in the Sustainability Beauty Awards for SustOleo™ MCT, a natural palm-free sensory ingredient alternative that contains 100% USDA certified biobased content; and the 2014 Frost & Sullivan Global Personal Care Product Innovation Leadership Award for Emulsense™, a cationic agent for hair conditioning and skin care that contains 100% USDA certified biobased content.


INOLEX is an independent, global specialty ingredients company that delivers natural, sustainable, and innovative technologies for health, beauty, and wellness. Guided by the Principles of Green Chemistry and lifecycle thinking, INOLEX balances technology and nature to create sustainable, life ingredients. The company delivers emerging ingredients across all major beauty care categories, focusing on new bio-based technologies that are authentically traceable and independently certified. Core technologies include Alternative Preservation; Highperformance Polymers for Sun Care; Alternatives for Silicones; Natural and Quat-free Cationic Conditioning Agents; and Palm Alternatives, with a focus on plant-based, certified natural options in all categories.

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