ADAPTONYL® is a natural anti-stress active ingredient obtained from an Ayurvedic plant, ashwagandha, capable of acting on all cutaneous exposome factors. In 2022, SILAB offers a more transversal approach to its protective active ingredient launched in 2006, with additional efficacy data in vitro and in vivo.

Cellular protection against the exposome

The skin is particularly exposed to environmental stresses (temperature changes, solar aggression, air pollution) and those related to lifestyles (poor diet, smoking, psychological stress, lack of sleep). Clustered under the term of cutaneous exposome, all these factors profoundly interfere with skin homeostasis thus contributing to its aging, as shown by SILAB’s novel modeling study.

ADAPTONYL® acts on all cutaneous exposome factors, whether environmental or lifestyle-related. Faced with the harmful effects on the epidermis and the dermis, it attenuates markers of oxidative and inflammatory stress, and restores cell metabolism.

Anti-stress effect on the skin

The cosmetic efficacy of ADAPTONYL® is rapid, as of 14 days of application, and has been demonstrated on a panel of volunteers selected for their particular exposure to the exposome, and their dull complexion.

ADAPTONYL® formulated at 2% reinforces the barrier function and improves the cutaneous microrelief. The active ingredient also refines skin grain and revives complexion radiance. These effects are confirmed by the volunteers who are more than 85% to find their skin smoother, more resistant and radiant.

An Ayurvedic plant with adaptogenic properties

ADAPTONYL® is composed of oligosaccharides, obtained from the roots of ashwagandha (Withania somnifera). This small shrub is used in traditional Ayurvedic medicine, in particular for its adaptogenic properties of resistance to stress (rasayana plant).

SILAB has chosen a secure supply from India, the cradle of Ayurveda. This supply chain is traceable to the plot and complies with the requirements of ABS (Access and Benefit Sharing) regulations in the framework of the Nagoya protocol. 

As a result of its transversal action against the cutaneous exposome, ADAPTONYL® is recommended in all protective care products at the amount of 1 to 4%. Available in aqueous solution, it is easy to formulate. It respects biodiversity regulations and has a natural origin content of 99% (ISO 16128). It is compliant with international cosmetic regulations (Europe, United States, China, Japan, etc.).


World leader in the engineering of natural active ingredients
SILAB’s reputation is based on excellence. An expert in skin biology and in the mastering of nature and biotechnologies for more than 35 years, this independent French company provides major names in cosmetic and dermo-cosmetic industry with patented and effective active ingredients.

The beauty of healthy skin
SILAB Cosmetics markets a catalog of almost 100 cosmetic natural active molecules, with scientifically proven functional properties complying with international regulations. They are recognized on the global beauty market for their high level of scientific innovation.

The care of compromised skin
SILAB Softcare, a department fully dedicated to the care of compromised skin, has a strong commitment to health. Intended for the dermo-cosmetic and dermatological markets, its active ingredients respond to cutaneous disorders (atopic dermatitis, acne, etc.) by reactivating the biological mechanisms of healthy skin according to three principles of excellence: Efficacy, Safety and Naturality. 

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