Richness in bioguided sulfur-containing peptides 

Sulfur-containing peptides are molecules known for their transversal ability to limit melanogenesis. For its new depigmenting active ingredient LIGHTSKIN®, SILAB has selected the yeast Ogataea siamensis, whose natural capacity to produce sulfur-containing molecules constitutes a considerable selective advantage for its development in the phyllosphere of the medicinal plant Ervatamia coronaria.

This potential was then enhanced by SILAB which decided to use its 15 years of expertise in biotechnologies to develop a unique process for bioguiding this yeast, specifically stimulating the production of large quantities of these molecules of interest. 

A depigmenting action doubled

This richness in bioguided sulfur-containing peptides enabled the global depigmenting action of LIGHTSKIN® to be doubled on Caucasian and Asian melanocytes, significantly limiting tyrosinase activity and melanin production. 

This efficacy was also demonstrated in pro-pigmenting contexts of pollution (receptor related to pollution (AhR) inactivated) and glycation (expression of the receptor for AGEs inhibited).  

Cosmetic benefits in Caucasian and Asian volunteers

LIGHTSKIN® was evaluated in volunteers selected on the presence of pigment spots, and more specifically on their high level of AGEs (Caucasian panel) or their history of living in polluted environments (Asian panel). The results showed that the active ingredient at 2.5% reduces the appearance of spots after 56 days of treatment on both panels. Uniformity of the complexion is thus improved, and radiance is revived. 91% of Asian volunteers stated that their complexion was more uniform and brighter, and their spots less visible.

With its targeted performance, LIGHTSKIN® is a patented active ingredient recommended in all depigmenting care products at the amount of 0.25 to 2.50%. Available in aqueous solution, it is easy to formulate. It complies with biodiversity regulations and has a natural origin content of 98.8% (ISO 16128). It meets international cosmetic regulations requirements (Europe, United States, China, Japan, etc.).

World leader in the engineering of natural active ingredients
SILAB’s reputation is based on excellence. An expert in skin biology and in the mastering of nature and biotechnologies for more than 35 years, this independent French company provides major names in cosmetic and dermo-cosmetic industry with patented and effective active ingredients.

The beauty of healthy skin
SILAB Cosmetics markets a catalog of almost 100 cosmetic natural active molecules, with scientifically proven functional properties complying with international regulations. They are recognized on the global beauty market for their high level of scientific innovation.

The care of compromised skin
SILAB Softcare, a department fully dedicated to the care of compromised skin, has a strong commitment to health. Intended for the dermo-cosmetic and dermatological markets, its active ingredients respond to cutaneous disorders (atopic dermatitis, acne, etc.) by reactivating the biological mechanisms of healthy skin according to three principles of excellence: Efficacy, Safety and Naturality. 

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