Focusing our efforts on natural product chemistry, Active Micro Technologies has combined cosmetic functionality with antimicrobial activity to develop a product range of multi-functional ingredients. This sustainable, nature-based product line includes aqueous, oil soluble, anhydrous and powder treatment materials that can reduce or eliminate the need for conventional preservatives. 

AMTicide® VAF (Propanediol & Bacillus Ferment & Saccharomyces Ferment Filtrate) is an antimicrobial active developed by co-fermenting Bacillus subtilis with Saccharomyces boulardii in a defined growth media. US Patent 11,193,147 describes this co-ferment as an antimicrobial agent, which can prevent or inhibit fungal growth within an area of a closed container housing a product. 

Many alternative preservatives are non-volatile and cannot evaporate to prevent the microbial growth associated with packaging. Packaging is a critical component for the successful preservation of personal care products. For a variety of packaging options, including jars, ensuring that the packaging headspace remains free of contamination is essential to prevent contamination of the entire formulation. 

Bacillus spp. are well-known rhizosphere residents of agricultural crops, including tomato, corn, and soybeans. This bacterium can produce non-volatile and volatile secondary metabolites that exhibit antifungal activity as a mechanism of biocontrol to prevent plant diseases caused by fungi. Saccharomyces boulardii is a probiotic strain of yeast, which can interact with other microorganisms. This co-inoculation captures an enhanced production of volatile compounds by the Bacillus cells. Through selective filtration techniques, the volatile organic metabolites are isolated and extracted to deliver a high potency volatile agent that delivers a moisturizing and antifungal activity for effective headspace protection. 

Active Micro Technologies Patented Technology - USPTO Patent: 11,193,147 

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