Clearing “zombie cells” in the skin

Formulation based on COSMOS approved ingredients.

Alpine Rose Active is a natural active ingredient based on an extract of organic alpine rose leaves and acts as a so-called senolytic. That means it specifically targets the senescent cells and not the healthy cells in the skin.

PhaseApplication / Trade NameINCI% w/w
A1 Aqua Aqua / Water 80.4
Konjac Mannan Gel Powder (GfN-Selco) Amorphophallus Konjac Root Extract 0.1
Xanthan Gum FNCSP-PC (Jungbunzlauer International AG) Xanthan Gum 0.1
GeoGard Ultra™ (Lonza) Gluconolactone (and) Sodium Benzoate 2.0
A2 Alpine Rose Active Rhododendron Ferrugineum Extract (and) Glycerin (and) Aqua / Water 2.0
Panthenol Panthenol 5.0
Glycerin Glycerin 5.0
Resplanta Phyto Pomegranate MB (Res Pharma Industriale) Punica Granatum Seed Oil Polyglyceryl-4 Esters  1.0
B CEGESOFT® PFO (BASF) Passiflora Incarnata Seed Oil 0.5
symbio®solv clear plus MB (Evonik Operations GmbH) Caprylyl/Capryl Glucoside (and) Aqua (and) Sodium Cocoyl Glutamate (and) Glyceryl Caprylate (and) Citric Acid (and) Polyglyceryl-6 Oleate (and) Sodium Surfactin 3.5
Perfume True Rain Blossom CO (Essencia AG) Sodium Benzoate 0.2
C Ronastar Red Lights (Merck KGaA)  Alumina (and) Titanium Dioxide (CI 77891) (and) Tin Oxide 0.1
YuraQ (Döhler) Phytelephas Aequatorialis Seed Powder 0.1

Manufacturing Procedure:

  1. Mix phase A1 under agitation until completely homogenous.
  2. Add Alpine Rose Active and the other raw materials from A2
  3. Stir until everything is dissolved.
  4. Mix phase B separately and then add it to phase A1 / A2 .
  5. Very important: stir slowly. Do not homogenize!
  6. Add components of phase C one by one under agitation.
  7. If necessary, adjust pH to 5.0 - 5.5 using NaOH or citric acid.


The information contained in this publication is provided in good faith and is based on our current knowledge. No legally binding promise or warranty regarding the suitability of our products for any specific use is made. Any statements are offered solely for your consideration, investigation and verification and do not relieve you from your obligation to comply with all applicable laws and regulations and to observe all third party intellectual property rights. Mibelle AG Biochemistry will not assume any expressed or implied liability in connection with any use of this information and disclaims any and all liability in connection with your product or its use. No part of this publication may be reproduced in any manner without the prior written permission of Mibelle AG Biochemistry.

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