GREENTECH launches a new innovative natural active ingredient : CIRCALYS®. Titrated in andrographolide sourced from an Ayurvedic plant, Green Chiretta, it efficiently reduces the impacts on skin and mood of fatigue induced by modern off-beat life.


Our new lifestyle habits are disrupting our natural rhythm. These changes in society are causing increasing fatigue for up to 45% of the population, especially for women. The circadian rhythms are like an inside clock. When off-beat life disturbs it, it influences almost all biological processes leading to a tired skin and impacting the mood.

Aware of these important repercussions, Greentech created CIRCALYS®, a potent active ingredient titrated in andrographolide, a molecule identified by Greentech scientists to counteract circadian disruption and revitalize skin. Inspired by Ayurveda, CIRCALYS® was developed from Green Chiretta (Andrographis paniculata), a major detoxifying plant in Ayurvedic traditional medicine.

CIRCALYS®: a chrono-detox feel good energizing active ingredient designed through chronobiological and psychobiological concepts. China & COSMOS approved, 100% natural origin (ISO 16128).


CIRCALYS® modulates skin rhythms, by restoring a “young” invigorating clock gene expression profile in old/tired skin cells and by acting on circadian modulators related to key cellular pathways. It extends cell longevity, reduces cell damages, promoting skin revitalization. CIRCALYS® also stimulates key signaling pathways connecting skin and brain, also influenced by circadian clock. It boosts oxytocin, endocannabinoid and endorphin signaling pathways to relax and protect skin from modern life impacts.


CIRCALYS® efficiently reduces the impacts on skin and mood of fatigue induced by modern off-beat life. Tested on night/shift workers during 28 days in a double blind clinical study, CIRCALYS® was proved to significantly reduce visible signs of fatigue : Eye bags, dark circles and under-eye wrinkles. Volunteers also found their skin more radiant, comfortable and rested.

Thanks to 3 scientifically recognized psychological tests, the use of CIRCALYS® in a cosmetic formula was also proved to significantly modulate the impacts of fatigue on mood : boosted feeling of well-being, reduced perceived stress and negative affect («yoga-like» effect).

GREENTECH Group is an international biotechnology company present on all continents and including 4 companies, GREENTECH, GREENSEA, BIOVITIS and MAPRIC in Brazil. A pioneer in plant biotechnology, GREENTECH develops and produces high-tech active ingredients from the plant, marine and microbial worlds for cosmetics, pharmaceuticals and nutraceuticals. This group comprises 200 people, 30% of whom are dedicated to research. GREENTECH collaborates with local producers for the establishment of long-term cooperation, with mutual benefits.
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