If we have a look at beauty standards and criteria and think about what is consider beautiful, we can see that over the decades these have changed. Maybe they have not only change but adapt to the different trends of that decade. 

Nowadays, body’s perfection is multi-faceted. Beauty standards are being shattered so everyone can embrace their body’s shape according to their own beauty standards, because loving yourself is the most fabulous of all revolutions. 

This movement is the “body positive beauty” which promotes body diversity to find the shape that improves your self-esteem. LipoTrue™ embraces this movement and brings you an active ingredient that allows you to find the shape that boosts and improves your self-esteem, Silstem-U™. 

Silstem-U™ (INCI: Silybum Marianum Extract, Arctostaphylos Uva-Ursi Leaf Extract) provides you the perfect solution, a combination of an extract of stem cells of Silybum marianum & the leaves’ extract of Bearberry. This active ingredient comes from the newly launched technology platform LipoTrue Greenbeat™, a botanical platform that encompasses botanical extracts and a stem cells technology called Greenology, to develop the future green active ingredients. 

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Silstem-U™ is a botanical extract with 100% natural origin according to ISO16128, Cosmos approved, halal certified, and also, vegan suitable

So how Silstem-U™ mechanism of action works? 

Under cold/exercise conditions there is a release of neurotransmitters into naturally innervated adipose tissue. This process induces NRG4 adipokine secretion by adipocytes which activates the thermogenesis process where fat is burned and heat is produced.

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Silstem-U™, is a green active ingredient that mimics the action of neurotransmitters, in acting directly on innervated adipose tissue. Therefore, Silstem-U™ enhances the release of NRG4, which improves adipose tissue innervation and initiates the browning process of white adipocyte into brown/beige adipocyte to activate lipolytic functions, and then, induce a slimming effect and reduction of cellulite.  

Slstem-U™ proved in vivo to reduce thigh circumference -0.9 cm vs placebo in 56 days and up to -1.6 cm thigh circumference in 2 weeks. Regarding the abdomen, Silstem-U™ showed to reduce an average of -0.9 cm and -1.3 cm, and up to -3.5 cm and -3.8 cm in 28 and 56 days respectively. 

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Silstem-U™ is able to reduce abdomen (40 years old volunteer) and thigh (33 years old volunteer) circumference in 28 days and 56 days in purple, respectively

About LipoTrue S.L.

LipoTrue™ moves a step up into the world of technologies, developing novel active ingredients by acting as a central R&D engine integrating high technological platforms. 

These high-tech platforms that LipoTrue manages for the rapid generation of the next active ingredients are: the use of Wild Plants as Biofactories for synthetic proteins synthesis, Big Data Analytics, in silico and biomimetic design of new peptides, Marine bio-research and LipoTrue Greenbeat™. LipoTrue™ is a new project with a solid scientific team of 30 multidisciplinary specialists, with an average cosmetic experience of more than 10 years. 

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