A revolutionary anti-aging concept, senolytics, has entered the medical world. Demonstrating remarkable results in early trials, senolytics can provoke rejuvenation in various tissues by specifically eliminating senescent cells without harming healthy cells. This concept has now been adapted for the cosmetic industry, by targeting and eliminating senescent fibroblasts in aged and photo-aged skin. To optimally complete skin rejuvenation however, the eliminated fibroblasts must be replaced with new cells – a feat that can be achieved by the activation of dermal stem cells. This revolutionary idea has been realized with the innovative ingredient concept SenoCellTecTM.