Efficacy of Natural ((-) isomer) Alpha Bisabolol and its Sustainable Supply Chain versus Synthetics Chemicals

G. Rocha, F. F.J. Batistela, R. Tomazini Candido

The aim of this study was to compare the effectiveness of both active versions: nature ((-) isomer) and synthetic (racemic mixtureThe aim of this study was to compare the effectiveness of both active versions: nature ((-) isomer) and synthetic (racemic mixture(±)) α-bisabolol in the treatment of skin and scalp. Natural version has advantages like being farnesol free, to have theproduction chain completely transparent and sustainable, in addition of the action potential guaranteed by the presence of thebiologically active, that is, the negative isomer (-) in 100% of the composition. Synthetic products, although it is claimed to besimilar to natural in the market, have a number of inherent manufacturing problems, such as production being dependent onenvironmentally and humanly harmful chemicals, difficulty in purification (i.e. product without trace of these compounds), andlow efficacy. Furthermore, it is known that micro-organism-dependent technologies are naturally low in yield, requiring highconsumption of chemical and biological reagents, which is in disagreement with modern industrial production techniques, interms of resource savings and natural goods.On the other hand, the active α-bisabolol: natural ((-) - α-bisabolol) from Candeia tree has been used by the market for decades,with no correlated effects on its use, dissimilar to the synthetic or similar products, with less time in the market, with unknownlong-term adverse effects.

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