Sunscreen producers and UV filter manufacturers are currently facing urgent challenges. On the one hand, the legal situation of two widely used UVB filters Ethylhexyl Methoxycinanamte (EHMC) and Octocrylene (OCR) is unclear due to rising concerns on their safety for humans and the environment; on the other hand, the image of nano particulate UV filters is downgraded in the press and by digital apps questioning their safety profile without scientifically based evidence. Some producers pro-actively remove these UV filters from their new sunscreens’ developments which is a real challenge in terms of performance achievement. This paper aims to provide UV filter system alternatives for developing efficient sunscreens without EHMC and OCR. Additionally, it clarifies the safety situation of nano-particulate UV filters and explains their usefulness in sunscreens, providing, however, UV filter system alternatives. Furthermore, this manuscript presents a calculation method to assess the impact of a UV filter combination on the environment and shows that it is possible to develop eco-sustainable sunscreens. Though, each restriction in the choice of UV filters will imply certain compromises.