Author R. Reynaud, Y. Rolland, B. Sennelier-Portet, A. Scandolera, M. Pélican, M. de Tollenaere, E. Chapuis
Journal Edition sofw journal 05-2021

Abstract

Derived from the green fractionation of mango leaves, Mangixyl™ (also referred as ‘Mangifera Indica leaves active’) is an effective cosmetic ingredient that is microbiome-friendly with proven efficacy targeting oil skin through sebum regulation. The cosmetic innovation activates specific receptors of gene’s pathway normally regulated by the highly potent retinoic acid.

In an era where sustainability and traceability are top of mind for consumers, the sourcing story of Mangixyl™ highlights our commitment to our Company Purpose. The mango leaves are collected in collaboration with the Association Bendia, based in Koro village (Burkina Faso, Africa). The association is a women-led initiative to contribute to the improvement of the living conditions of the community. Thus, Mangifera Indica leaves active is an ingredient good for the consumers, good for the planet and good for the people.This ingredient aims to relieve consumers from the discomfort caused by oily skin. It activates some receptors of the retinoic acid-regulated genes pathway and decreases in vitro, ex vivo and in vivo the synthesis of lipids on all skin ethnicities. Additional clinical data showed efficacy against prone-to-acne skin, and on the regulation of sebum on scalp hair. Amidst the current COVID-19 crisis, it also provides an effective response to the “maskne” phenomenon which has been gaining momentum lately.

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