The cosmetic industry is continuously seeking for innovative and reliable products. For generations, collagen has become one of the most trustworthy ingredients due to its efficacy and its interesting properties: anti-aging, moisturizer, humectant, among others. Substantiated concerns have been raised with regard to quality, safety and consistency of animal-sourced collagen. In this context, it has been developed a plant-based fragment of human type I collagen, which is of high purity and contains the proper post-translational modifications to be completely functional due to the use of wild-plant as biofactories’ technology. This identical-to-human fragment collagen type I has been shown to have broad efficacy in and tests, as well as a potent anti-aging effect in clinical studies. These interesting properties highlights fColI(h) as a highly effective and safer source of collagen in the very near future.