DE 
Abstract
Vascular blemishes can lead to unsightly skin appearance. A neglected cause can be oedema leading to puffy eyes and promoting visibility of small blood vessels. By taking advantage of an aqueous extract from Helichrysum italicum, puffy eyes and visibility of spider veins could be significantly reduced in an in-vivo study. Data from this study and in-vitro investigations suggest a negative role of nitric oxide (NO) in the development of these blemishes.
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