Botaneco Demonstrates High Protective Effects of Oleosome-based Sun Care Prototypes Containing 80% Less Sunscreen Actives than a Commercial Formulation


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Lambertville, NJ - February 13, 2018
A study using in vitro reconstructed human tissues (MatTek Epiderm) to measure the influence of UVB radiation on inflammation markers show oleosome-based sun care formulas function with high protection effects, using a minimal amount of sun care actives.

Formulating sun care products to prevent skin inflammation markers from rising - the critical indicators of sunburn - usually requires a relatively high loading level of UV filters.  A new study examining the influence of UVB radiation on various inflammatory signs shows that it is possible to prevent these markers from rising using 80% fewer sunscreen actives than a commercial SPF 30 formulation [1].

Employing in vitro human tissues reconstruction (MatTek EpiDerm™) and treating the tissues with a small amount of prototype oleosome-based SPF 30 formula, or commercial SPF 30 beach product, indicate that both formulas, following 300 mJ/cm2 of UVB irradiation, demonstrate an ability to inhibit primary inflammatory markers.

"The results support previously reported clinical results that show oleosome-based sun care formulations function with high protection effects with significantly less sun care actives," said Vince Gruber, Chief Innovation Officer, Botaneco, and lead author.

When organic UV filters are combined with safflower-based oleosomes and placed into finished skin care formulations, the final formulations maintain SPF 30 levels, using only 20% of UV actives typically found in US commercial products [2]. 

The reasons for this benefit are not entirely known, but it is believed that organic sunscreen actives chemically associate with oleosomes, which are naturally loaded with safflower oil.  When the oleosomes are applied onto the skin, as they dry, the oleosomes rupture and the oil within the oleosomes rapidly spreads in a very thin film across the skin.

"It is felt that this rapid spreading creates a very thin film of the sunscreen on the skin, but one with homogeneous skin coverage that allows for significant reductions in required UV actives," said Gruber.

The latest study, "In Vitro Examination of an Oleosome-based Sun Protection Product on the Influence of UVB-Induced Inflammation Markers in Reconstructed Tissues," shows that the UV actives loaded oleosome-based sunscreens have clear benefits in preventing the known
upregulation of the gene expression of specific inflammatory markers, such as IL-1α, IL-6, IL-8, and PGE2, from the application of UVB energy. 

Natural oil and protein storage vesicles
Oilseeds, like safflower and sunflower, store oil in small encapsulation vehicles called oleosomes. The oleosomes are triglyceride oils surrounded by a phospholipid shell and enshrouded in unique proteins called oleosins.

"Oleosomes from Botaneco's oilseed extraction processes are finding multiple uses in personal care, in that they remain fully intact, making the oil within the oleosome less susceptible to oxidation," said Kathy Mish, Marketing Manager, Botaneco."

"We found that organic actives can be loaded into an intact oleosome, in a way that allows the sunscreen agents to work efficiently upon application to the skin. Reducing the actives required for optimal sunscreen efficiency, using only a natural ingredient, is in line with consumer requests for new sun care formulas, such as daily wear SPF moisturizers," Mish said.

For more information about the study, and to request sun care formulas containing oleosomes, visit Botaneco on the web at botaneco.com.


About Botaneco
Botaneco, headquartered in Calgary, Alberta, adds performance and value to personal care products with highly functional components of oilseeds. Through a proprietary, gentle extraction process that alleviates the need for conventional crushing, heat, and chemicals, Botaneco sustainably harnesses the oleosomes and proteins of safflower and canola to provide products in their original, natural state. The company’s new Sustainability Center of Excellence in New Jersey (USA) serves as a resource to optimize sustainable technologies in personal care.

1. In Vitro Examination of an Oleosome-based Sun Protection Product on the Influence of UVB-Induced Inflammation Markers in Reconstructed Tissues. Journal of Photochemistry & Photobiology, B: Biology 179 (2018) 39-45
2. Sustainable extraction of nature's oil and protein storage vesicles, INFORM: 28 (2017) 28-31


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