The oxygen we breathe with our lungs is used by all our body’s cells including skin cells. This cell respiration process is essential to their survival. Specifically, oxygen is used by mitochondria, the cell’s powerhouse, to produce energy and water, to ensure optimal functioning of vital metabolisms such as hydration, regeneration, protection, and cell proliferation.

Hypoxiageing™ is tissue ageing induced by cell hypoxia. It is a rising skin concern because of pollution. Although the skin is very poorly permeable thanks to its multi-lamellar structure, a certain number of entry routes exist, particularly via the pores and the capillary infundibulum. Once deposited on the skin, the microparticles found in polluted atmosphere deliver the molecules adsorbed on their surface which can thus penetrate even through healthy skin thanks to their small size, their lipophilic nature and the drop in quality of the barrier function of the epidermis. The absorption of these microparticles causes toxic effects on cellular components and in particular, a deficit in the supply of oxygen.

Lack of oxygen or hypoxia causes the cell to return to its old mode of energy production without mitochondria, called fermentation. This is 18 times less effective. This alteration in cell respiration induces premature skin ageing together with dull, dry, and devitalised skin.

More and more beauty salon offers oxygen therapy to counteract hypoxiageing™ but a cosmetic solution should be able to answer this increasing needs.

To address hypoxiageing™, the first step consists of improving cell respiration and energy production, necessary for optimal cell functions. The second one is detoxifying the cells from micropollutants to protect mitochondria and reduce cell oxidative damage. And the third one is about cell regeneration especially to ensure skin barrier reinforcement as pollution induces barrier function disruption and dysbiosis.

SEDERMA has developed an active ingredient of marine origin allowing, like an exercise, to stimulate the production of energy by skin cells, to strengthen the barrier function of the epidermis, to stimulate the depollution mechanisms and allows to restore all its radiance to the skin in particular by promoting hydration of the skin and its smoothing.

Stay connected to be among the first to benefit from this innovative and sustainable ingredient which protects the skin from pollution and combats hypoxiageing™. More to come in a few weeks!

Stay connected at www.sederma.com

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