Biotechnologically Produced Moss Active Improves Skin Resilience

F. Wandrey, B. Henes, F. Zülli, R. Reski

Mosses substantially helped changing primitive earth into a green planet before vascular plants even existed. They encodeMosses substantially helped changing primitive earth into a green planet before vascular plants even existed. They encodegenes and proteins for extraordinary resilience long abandoned by higher plants. Biotechnology offers a sterile productionof the moss Physcomitrella patens in a reproducible and sustainable way. MossCellTec™ No. 1 is the first biotechnological mossbasedproduct for cosmetic application.In our research, we have investigated the importance of cell nucleus health as a novel target for anti-aging cosmetics. Interestingly,the moss extract was able to improve the expression of cell nucleus health markers in aged skin cells. Additionally,the active ingredient could improve the hot-humid/cold-dry adaptation of reconstructed skin and improved skin homogeneity,barrier and hydration despite stressful weather conditions in a placebo-controlled clinical study. The moss active may thereforeenhance the general resilience of the skin against environmental changes.

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