E. Besic Gyenge, S. Hettwer, B. Suter, S. Breitenbach, B. Obermayer
Our intracellular cleaning system is one of the most sophisticated mechanisms in our body. The long-lived skin cells such as fibroblasts and basal layer keratinocytes keep themselves and their environment clean and tidy every day through autophagy.
This cellular self-digestion process is not only vital for cleaning the cells but also for maintaining cellular homeostasis and physiological cellular function.
Unfortunately, the efficiency of the cellular waste disposal systems deteriorates over time. Cells lose their functional identity, resulting in cellular senescence. Therefore, safely inducible autophagy and maintenance of proper autophagy processes will help to counteract age-accumulated impairments and keep keratinocytes and fibroblasts young.
REFORCYL®-AION targets the three major components involved in a healthy cellular cleaning process: the Golgi apparatus, the LC3 autophagy marker protein and mitochondrial fitness.
It helps cells to reactivate the autophagy process, it supplies them with the necessary nutrition and its whole supply chain is carbon-neutral.
It is thus a holistic concept that is both skin- and nature-friendly.