The Ministry of Science and Innovation of Spain has granted a loan of 334 thousand euros to Vytrus Biotech, specialized in plant stem cell cultures, and a non-refundable grant of 160 thousand euros to GAIKER Technology Centre, a member of the Basque Research & Technology Alliance (BRTA). The project, planned to be carried out in 3 years, aims to develop a new generation of plant-based skin treatments, with applications in the pharmaceutical and cosmetic industry.

This research arises from the need to continue investigating the skin, the largest organ in the human body. The skin is exposed to constant attacks from our environment (pollution, sun excess, etc.) and to dermal products of chemical origin with adverse side effects (allergies, irritations, or dermal pathologies). About a third of the world's population has skin conditions to be treated and the number is increasing due to environmental degradation and the proliferation of synthetic products that increase the cases of allergies and other skin pathologies.

Vytrus Biotech, which develops cosmetic active ingredients based on plant stem cells, proposes to address the treatment of the skin through a revolutionary plant mechanism of action: Quorum Quenching. Plants have Anti-quormonas molecules that, when applied to human skin, can block the communication between skin bacteria to prevent their virulence, and from causing pathologies and affections.

The "Retos" project consists of the design of active ingredients rich in these Anti-Quormones, to disarm bacteria by hacking their communication systems, in the same way that plants do. Useful to treat and prevent skin pathologies in a way that respects its ecosystem, since microbes are not destroyed nor threatened, but are kept in balance.

To demonstrate this efficacy, GAIKER will develop human skin models in the laboratory that do not currently exist on the market and will allow the study of the different applications of interest. In this way, it aims to develop postbiotic products of natural origin for cosmetic applications such as sensitive skin and pharmaceuticals for different dermatological conditions. The potential market to which the products developed in the "Retos" project are directed could be around 10 million euros per year. Thanks to the results of this project, it will be possible to reduce public spending on the sanitary system, contribute to the development of sustainable technology, increase an industrial fabric with high added value, as well as improve the competitiveness of the project's member companies.

The products will be commercialized through the international network of Vytrus Biotech

Products indicated for sensitive skin and new preservatives of biological origin will be commercialized through Vytrus Biotech's own international network, with sales in 24 countries and distribution agreements in more than 50. Vytrus Biotech has contracts in force and agreements of collaboration with Spanish and international pharmaceutical multinationals, a situation that gives it a preferential position for the generation of an international partnership that guarantees the commercialization of the products generated in this project for the medical skin care sector.

Vytrus Biotech is a company specialised in the development, production and commercialization of high added value active ingredients based on plant stem cell culture technology for cosmetic and dermocosmetic industry. Positioning as a pioneer in the use of this technology for business purposes gives Vytrus Biotech a solid foundation on which to build a sustainable competitive advantage. Through this technology, it is possible to obtain natural, patentable and efficient products. Vytrus has a team of more than 20 employees in its headquarters in Terrassa (Barcelona, Spain) and is present in Europe, USA, LATAM and Asia, among others, through its international network of distributors.
The biotech company has been awarded with ‘Best Ingredient Award’ worldwide at In-cosmetics Global 2020 for its two new ingredients: Kannabia Sense and Deobiome Noni.
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GAIKER, member of Basque Research & Technology Alliance, BRTA, is a private and non-profit organisation devoted to research and offering innovative technological solutions for corporations. Since its inception in 1985, it contributes to the technological development and competitiveness of businesses through learning and specialisation and ultimately transferring technologies related to their areas of knowledge: Biotechnology and Sustainable Composites and Functional Polymers.

From its Biotechnology area, the Center conducts in vitro and ex vivo preclinical studies aimed at the toxicological, pharmacokinetic and functional evaluation of compounds (including active principles, drugs, cosmetics, functional ingredients and nanocomposites), for which it has the Certificate of Compliance of GLP (Good Laboratory Practices). Likewise, it is an expert in the development of biodetection and industrial biotechnology focused on improving industrial processes.

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