From October 21-30, BASF and its research partners will give four podium presentations and lead six poster sessions about cutting-edge research in Personal Care.
Topics cover a wide range of recent research projects related to innovative skin and hair care solutions.
The event will be hosted in Yokohama, Japan, and will be held in a virtual format for the first time due to the ongoing Covid-19 pandemic.
Experts from BASF will share insights into their recent innovative research activities at the thirty-first Congress of the International Federation of Societies of Cosmetic Chemists (IFSCC) from 21 to 30 October 2020. For the first time ever, the event will be held virtually to protect the safety and health of the scientific community during the Covid-19 outbreak. Instead of holding live presentations, video recordings and supporting material will be made available for participants to download on-demand for the duration of the congress. Representatives from BASF and its research partners will hold four podium presentations and lead six poster sessions.
The world’s first 3D bioprinted immune skin model
A solution for rapid and reliable testing of products addressing reactive skin will be presented in a podium session. There is a strong need for better testing systems showing how ingredients or finished products affect or can improve sensitive or allergic skin. Scientists from BASF and its partner CTIBiotech have developed a 3D full-size bioprinted model of human skin that contains immune system cells such as macrophages. Testing has demonstrated that this model is suitable for screening molecules and ingredients for inflamed skin conditions like Atopic Dermatitis.
Using iPSC technology to create a 3D autologous hair bulb model
A new 3D model of the cellular interactions between ectodermal and mesodermal cells in human hair follicles will also be presented. These interactions control hair cycle, growth, shaft quality and pigmentation. Current animal models do not reflect human physiology and 2D in vitro cultures cannot reflect in vivo mechanisms. This creates high demand for a 3D model that can be used to study the hair follicle and validate new active ingredients. BASF has worked together with TissUse GmbH in Berlin, Germany, to create an in vitro 3D hair bulb model based on three cell types derived from induced Pluripotent Stem Cells (iPSCs). The resulting model has a structure very close to the in vivo hair bulb and has delivered promising results.
A new 3D microbiotic skin model for Atopic Dermatitis
In addition, BASF experts are going to share their findings from research into a Reconstructed Human Epidermis (RHE) model that is able to mimic the impairments of the skin barrier observed in Atopic Dermatitis (AD). In recent years, in vitro models have been developed that can reproduce some of the pathophysiological features of this increasingly common condition – but not all of them. BASF and its partners from Toulouse University, France, have developed an RHE model that is able to better mimic the impairments of the skin barrier observed in AD at the physical, microbial and immune levels. This new model has strong potential for in vitro screening of cosmetics or therapeutic compounds for AD.
In a fourth podium session, new findings on the beneficial effects cosmetic emollients can have on dehydration induced mechanical stress in the skin will be presented. Emollients are widely used in skin-care formulations for a number of reasons, e.g. they help to keep skin feeling soft, smooth and moisturized, and are also used to modulate formulation characteristics such as spreadability and haptics. However, little is known about how the molecular structure and chemical functionality of an emollient affect the barrier and biomechanical properties of the human stratum corneum. Scientists from BASF and Stanford University have generated new insights on potential effects of emollients on skin barrier function, hydration and biomechanics. BASF will be able to leverage these insights to develop new and improved skincare solutions based on its broad emollient portfolio.
Poster sessions exploring several exciting research projects
On top of the four podium presentations, R&D teams from BASF will provide six poster sessions that share findings from a range of projects. The topics covered will include a new in vitro method for evaluating the effect that anti-pollution rinse-off products have on the hair’s natural oil, sebum. Another session will explore two methods of tackling the negative effects of airborne pollen on the skin and hair. In addition, representatives from BASF will present insights into a droplet-based microfluidic testing method that can be used to screen the impact of cosmetic ingredients on microbial communities in the skin.
Poster sessions led by BASF will also discuss a new hydrogel composition that delivers enhanced freshness and lightness sensations without compromising on the texture or rheological properties of the formulation. Another BASF team will describe a new reactive conditioning approach to improving the mechanical strength of hair fibers by triggering a Maillard reaction in hair fibers. Lastly, one session will deal with an original clinical protocol that has been used to evaluate the emotional experience of consumers when applying a cream for dry and sensitive skin that contained a novel molecular patch.